AlphaFold
No written verdict yet. Here is what commenters said.
13recommend
4warn against
Nov 30, 2025first mention
Sep 6, 2026latest mention
Why people recommend it
“AlphaFold is great...to come up with a starting model for a chimeric fusion or something.”
structural biologist at a mid-sized biotechon “So How Is AI Drug Discovery Doing, Really?”
Show 3 more
“protein folding has been figured out by AI”
“Deep learning: https://en.wikipedia.org/wiki/AlphaFold”
“I like how you're trying to argue with the Nobel committee here.”
Caveats and dissent
“these folding models fail when we don't have crystal structures”
“This does reveal the weakness of AlphaFold approaches”
Show 2 more
“hours on AlphaFold queue”
“It revealed a very linear data pipeline stuffed with steps of O(N)^6 algorithms.”
Often compared with
Who recommends it in their own words
Threads where it came up
- Why proteins fold and how GPUs help us fold 3 mentions
- SETI@home: Data Acquisition and Front-End Processing 2 mentions
- An Alien Mind 1 mention
- Amodei Re. Regulation 1 mention
- So How Is AI Drug Discovery Doing, Really? 1 mention
- Grok Bot by SpaceXAI 1 mention
Also written as AlphaFold 3, AlphaFold2, AlphaFold 2. Data: alphafold.json. Quotes are verbatim; the verdict and theme labels are written by a model from these comments, and every clause links to its sources.
All comments 23
“AlphaFold being an exception”
“these folding models fail when we don't have crystal structures”
“AlphaFold is great...to come up with a starting model for a chimeric fusion or something.”
“Does AlphaFold since 2018 (from Google, and now as the Google spin-off Isomorphic Labs under Demis Hassabis) count?”
“protein folding has been figured out by AI”
“Deep learning: https://en.wikipedia.org/wiki/AlphaFold”
“Google DeepMind disbands its Nobel-prize winning AlphaFold team”
“AlphaFold 3 inference pipeline”
“I like how you're trying to argue with the Nobel committee here.”
“Alphafold2 was great but didn't actually 'solve' protein-folding”
“This does reveal the weakness of AlphaFold approaches”
“Literally saved his dog's life.”
“hours on AlphaFold queue”
“It revealed a very linear data pipeline stuffed with steps of O(N)^6 algorithms.”
“AlphaFold is an amazing machine learning approach to predicting protein structure”
“Wasn't this largely solved by DeepMind's AlphaFold?”
“more than doubles the accuracy of AlphaFold 3”
“Maybe along the lines of alphafold 3”
“it is a highly unique architecture and approach”
“Physical models are baked right into AlphaFold models and development at multiple steps”
“See for example the AlphaFold2 presentation linked here”
“AlphaFold solved protein folding.”
Didn’t the transformer model come from AlphaFold? I feel like we wouldn’t have had the LLMs we use today if it wasn’t for AlphaFold.